Description |
protein kinase N2 |
NEDD4 E3 ubiquitin protein ligase |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
- Coronary artery disease ( 29212778)
- Diastolic blood pressure ( 27841878)
- General risk tolerance (MTAG) ( 30643258)
- Heel bone mineral density ( 30598549 28869591)
- Height ( 20881960 25282103 31562340)
- Intraocular pressure ( 29617998)
- Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
- Narcolepsy ( 23459209)
- Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095)
- Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
- Periodontal microbiota ( 22699663)
- Photic sneeze reflex ( 27182965)
- Pulse pressure ( 27841878)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Response to fenofibrate (LDL cholesterol levels) ( 27002377)
- Rosacea symptom severity ( 29771307)
- Serum protein levels (sST2) ( 23999434)
- Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
- Systolic blood pressure ( 30224653 27841878)
- Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
- Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
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Interacting Genes |
18 interacting genes:
AKT1
CASP3
CCDC136
CHGB
EEF1A1
EIF3G
FAM193B
HDAC5
MAP3K2
MYO9B
NCK1
NCK2
NEDD4
PDPK1
PLCG1
PTPN13
RHOA
SUMO2
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238 interacting genes:
ABCB1
ABL1
ABL2
ADRB2
AKT3
AMOT
AMOTL1
AMPD2
ANKRD13D
ANXA13
AP1G2
ARID1A
ASPSCR1
AURKC
BAIAP2
BMPR1A
BRCA2
CAD
CALCOCO1
CAMK1D
CAMK4
CAMKK2
CASP1
CASP3
CASP6
CASP7
CBLB
CCNH
CDC25C
CDK5
CDK5R1
CLIC2
CLK3
CPSF1
CPSF6
CUEDC1
DAZAP2
DCUN1D1
DDX3X
DDX54
DHX30
DIAPH1
DVL1
DYRK4
EBAG9
EGFR
EPHA5
EPRS1
EPS15
ERBB3
ERBB4
ERMN
ERRFI1
FES
FGF12
FGF21
FGFR1
FGFR2
FKBP3
FLT1
FLT4
FYN
GABARAP
GABARAPL1
GABARAPL2
GBA
GFUS
GRB10
GRIN2A
GRK4
GRK7
H3-3A
HGS
HMCES
HNRNPK
HNRNPL
HNRNPU
HNRNPUL1
IFITM3
IGF1R
IRS1
IRS2
JHY
JUN
KCNAB1
KCNAB2
KCNJ16
KIFC3
LAPTM5
LATS1
LINC01198
LITAF
LUC7L2
MAP1LC3A
MAP1LC3B
MAP1LC3C
MAP3K2
MAP3K3
MAP3K5
MAP4K5
MAPKAPK3
MARK2
MARK4
MLANA
MOB3A
MRPL19
MTMR4
MYCN
MYO15B
N4BP2
N4BP3
NDFIP1
NDFIP2
NFE2
NHP2
NSRP1
NUDT21
NUMB
PARP16
PAX7
PDGFRB
PIP5K1A
PIP5K1C
PKN2
PLK1
PLK2
PMEPA1
POLR1C
POLR2A
POLR2B
POLR2C
POLR2E
POLR2M
POLR3A
PRKG2
PRKX
PRPF8
PRR16
PRRG1
PRRG2
PSMD4
PYM1
RAC1
RAD51AP1
RAF1
RANBP10
RAP2A
RAPGEF2
RAPGEF6
RASGEF1A
RASL11B
RBCK1
RET
RFT1
RNF11
RNF7
RPAP2
RPAP3
RPL18A
RPS3A
RPS6KA3
RPS6KA4
RPS6KB1
RUNX1
RUVBL1
SAAL1
SAMSN1
SAV1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SEPTIN9
SERTAD1
SFTPC
SGK1
SGK2
SH3KBP1
SHISA6
SHTN1
SIVA1
SLC23A2
SLC6A3
SMAD1
SMAD3
SMAD5
SMARCC1
SMO
SNCA
SP140L
SPANXN3
SPRY2
SRC
SRMS
SRSF7
STK24
STK25
STK26
STK31
STK4
SULF1
SYK
SYT1
TAF1B
TBC1D7
TBK1
TCEANC
TCP11L1
TEAD2
THOC1
THRAP3
TNIK
TOM1
TOM1L2
TP53BP2
TP73
TRIM44
TRIM52
TRPV6
TTYH2
UBAP2L
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2L3
UBE2M
UBOX5
URI1
VDAC2
VDAC3
WBP1
WBP2
WEE1
YES1
YOD1
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Entrez ID |
5586 |
4734 |
HPRD ID |
03972 |
03786 |
Ensembl ID |
ENSG00000065243
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ENSG00000069869
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Uniprot IDs |
Q16513
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P46934
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PDB IDs |
4CRS
4RRV
6CCY
6GBE
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2KPZ
2KQ0
2M3O
2XBB
2XBF
3B7Y
4BBN
4BE8
4N7F
4N7H
5AHT
5C7J
5C91
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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