SELENOS and ETV7

Data Source:
BioGRID (affinity chromatography technology)

		SELENOS	ETV7
Description		selenoprotein S	ETS variant transcription factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Integral Component Of Endoplasmic Reticulum Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Antioxidant Activity Enzyme Binding Signaling Receptor Activity ATPase Binding Ubiquitin-specific Protease Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Gluconeogenesis ER Overload Response Response To Glucose Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Cellular Response To Oxidative Stress Establishment Of Protein Localization Cell Redox Homeostasis Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Glucose Import Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Response To Redox State Cellular Response To Lipopolysaccharide Regulation Of Nitric Oxide Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Macrophage Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Platelet count ( 27863252) Rheumatoid arthritis ( 30423114) Systemic lupus erythematosus ( 28714469) White blood cell count ( 29403010)
Interacting Genes		9 interacting genes: APOA5 DERL1 GTF2IRD1 KLHDC2 KPNB1 MFHAS1 SAA1 SRPK2 VCP	5 interacting genes: IRF4 L3MBTL1 LRPAP1 VTN WT1
Entrez ID		55829	51513
HPRD ID		12133	16095
Ensembl ID		ENSG00000131871	ENSG00000010030
Uniprot IDs		Q6GYA4 Q9BQE4	Q9Y603
PDB IDs		2Q2F 5KIU 5KIY 6DO4
Enriched GO Terms of Interacting Partners?
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