VPS11 and RNF26

Data Source:
HPRD (in vitro)

		VPS11	RNF26
Description		VPS11 core subunit of CORVET and HOPS complexes	ring finger protein 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport	Endosome Organization Protein Ubiquitination Regulation Of Type I Interferon Production Negative Regulation Of Defense Response To Virus Protein K11-linked Ubiquitination Protein Localization To Perinuclear Region Of Cytoplasm
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)	Platelet count ( 32888494) Refractive error ( 32231278)
Interacting Genes		33 interacting genes: BCAR1 BMI1 ECPAS EZR GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B MSN RAB7A RDX RILP RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS39 VPS45	11 interacting genes: INCA1 STING1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2Q1 UBE2U UBE2W
Entrez ID		55823	79102
HPRD ID		12258	05842
Ensembl ID		ENSG00000160695	ENSG00000173456
Uniprot IDs		A0A087WXL6 B7Z879 Q9H270	Q9BY78
PDB IDs
Enriched GO Terms of Interacting Partners?
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