VPS11 and FUT1

Data Source:
HPRD (in vitro)

		VPS11	FUT1
Description		VPS11 core subunit of CORVET and HOPS complexes	fucosyltransferase 1 (H blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane	Golgi Apparatus Integral Component Of Plasma Membrane Membrane Golgi Cisterna Membrane
	Molecular Function	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Galactoside 2-alpha-L-fucosyltransferase Activity Fucosyltransferase Activity Alpha-(1,2)-fucosyltransferase Activity
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport	Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell-matrix Adhesion Carbohydrate Metabolic Process Protein Glycosylation Positive Regulation Of Endothelial Cell Migration Olfactory Bulb Development Regulation Of Cell Adhesion Fucosylation L-fucose Catabolic Process Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Pathways			ABO blood group biosynthesis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)	Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Bipolar disorder ( 21926972) Cooked vegetable consumption ( 32066663) Dietary macronutrient intake ( 23372041) Elevated serum carcinoembryonic antigen levels ( 24941225) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Intake of total sugars ( 31005972) Meat-related diet ( 32066663) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Processed meat consumption ( 32066663) Retinal vascular caliber ( 21060863) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		33 interacting genes: BCAR1 BMI1 ECPAS EZR GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MARK3 MON1B MSN RAB7A RDX RILP RNF181 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS39 VPS45
Entrez ID		55823	2523
HPRD ID		12258	07186
Ensembl ID		ENSG00000160695	ENSG00000174951
Uniprot IDs		A0A087WXL6 B7Z879 Q9H270	P19526 Q6IZA2
PDB IDs
Enriched GO Terms of Interacting Partners?
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