HR and C19orf54

Data Source:
BioGRID (two hybrid)

		HR	C19orf54
Description		HR lysine demethylase and nuclear receptor corepressor	chromosome 19 open reading frame 54
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Oxidoreductase Activity Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation
Pathways
Drugs
Diseases		Atrichia with papular lesions Localized autosomal recessive hypotrichosis Marie-Unna hereditary hypotrichosis (MUHH)
GWAS		Obesity-related traits ( 23251661)	Blood protein levels ( 28240269) Carotid intima media thickness (mean) ( 31801372)
Interacting Genes		35 interacting genes: AMMECR1 ATP23 C11orf1 C19orf54 CNFN CYSRT1 FAM168A GEMIN4 HDAC1 HDAC3 HDAC5 HMGB1 HOXA1 INCA1 KLHL20 KRTAP11-1 KRTAP13-2 KRTAP15-1 KRTAP3-1 KRTAP3-3 KRTAP6-3 MGAT5B PLA2G10 PRKCA RARA RARB RBP3 SPAG8 SPRY3 TBL1X TRIM27 TSC1 VDR YPEL3 ZMYND12	67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19
Entrez ID		55806	284325
HPRD ID		03808	13449
Ensembl ID		ENSG00000168453	ENSG00000188493
Uniprot IDs		O43593	Q5BKX5
PDB IDs
Enriched GO Terms of Interacting Partners?
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