C19orf54 and VAC14

Data Source:
BioGRID (two hybrid)

		C19orf54	VAC14
Description		chromosome 19 open reading frame 54	VAC14 component of PIKFYVE complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Extrinsic Component Of Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex
	Molecular Function		Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process		Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity
Pathways			Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Carotid intima media thickness (mean) ( 31801372)	Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061) Pulse pressure ( 28135244)
Interacting Genes		67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19	107 interacting genes: ABHD11 ACSS1 AMT APP ARID5A ASB13 BCL2L1 BHLHE40 C11orf54 C19orf54 C2CD6 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK CRYBA1 CRYBA2 DDAH2 EEF1AKMT3 EHHADH EIF2S1 EIF6 FAM50B FIG4 FNDC3B GABPB2 GALT GINS3 GLIS2 GNB1 GTF3C2 HDHD3 HNF1B HNRNPLL INTS11 JMJD7 KHDC1 KRT82 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LINC00518 LPAL2 MBLAC1 MEOX2 METTL15 MGAT5B MPPED2 MTMR9 MVP MYOZ1 NDUFAB1 NGB NOS1 NTAQ1 OIT3 OTOS PBLD PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PPP6C PRADC1 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX2 RHBDL1 RHOXF2 RIPPLY1 RNASEH2C RSKR SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TEX37 TP53BP1 TRIM55 TRIM63 UFSP1 VENTX VHLL WDR83 WRAP53 ZBTB49 ZCWPW1 ZNF34 ZNF720
Entrez ID		284325	55697
HPRD ID		13449	07660
Ensembl ID		ENSG00000188493	ENSG00000103043
Uniprot IDs		Q5BKX5	Q08AM6
PDB IDs
Enriched GO Terms of Interacting Partners?
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