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DCP1A and PAXIP1
Data Source:
BioGRID
(two hybrid)
DCP1A
PAXIP1
Description
decapping mRNA 1A
PAX interacting protein 1
Image
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
Membrane
Cytoplasmic Ribonucleoprotein Granule
Nucleus
Nucleoplasm
Chromosome
Nuclear Matrix
Histone Methyltransferase Complex
MLL3/4 Complex
Molecular Function
MRNA Binding
Protein Binding
Enzyme Activator Activity
Hydrolase Activity
Kinesin Binding
Enzyme Regulator Activity
Identical Protein Binding
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Positive Regulation Of Catalytic Activity
Regulation Of MRNA Stability
Exonucleolytic Catabolism Of Deadenylated MRNA
Protein Localization To Cytoplasmic Stress Granule
Positive Regulation Of Histone H3-K36 Methylation
Vasculogenesis
Double-strand Break Repair Via Nonhomologous End Joining
DNA Recombination
Response To Ionizing Radiation
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Histone Acetylation
Negative Regulation Of DNA-binding Transcription Factor Activity
Endothelial Cell Migration
Positive Regulation Of Isotype Switching
Positive Regulation Of Isotype Switching To IgG Isotypes
Histone H3-K4 Methylation
Positive Regulation Of Histone H3-K4 Methylation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Adipose Tissue Development
Chorion Development
Regulation Of Cell Cycle G2/M Phase Transition
Positive Regulation Of Response To DNA Damage Stimulus
Pathways
mRNA decay by 5' to 3' exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Electrocardiographic traits (
25055868
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Heart rate (
23583979
)
PR interval (
32439900
)
Refractive error (
32231278
)
Spontaneous preterm birth (preterm delivery) (
25599974
)
Bladder cancer (smoking interaction) (
24662972
)
Metabolite levels (
23823483
)
Interacting Genes
16 interacting genes:
AGO1
AGO2
DCP2
FHL2
LSM8
MAPK3
MIR15B
NSMAF
PAXIP1
PNRC2
RAD52
RITA1
SMAD4
TTF2
UPF1
YWHAG
91 interacting genes:
A2M
APP
ATP1B1
ATP1B3
BTBD16
BTBD6
C2orf42
CABYR
CATSPERG
CBX8
CCNDBP1
CIAO2B
CLU
COMTD1
CYB5R4
DCP1A
DIS3L
DNAJA1
DNAJB11
DYNC2H1
ECSIT
EIF3I
EIF5B
EP300
EPB41L3
FAHD1
FBLN5
FUCA1
H2AX
H3C1
HNRNPLL
HSPA14
HSPA4L
INTS7
LACTB
MAPRE2
MAST1
MRPL33
MT-ND1
MT2A
MTIF3
MTNR1A
NOS3
NPC2
NUPR1
NXT1
PAGR1
PAX2
PCBP2
PCYT1B
PGGHG
PGM1
PIAS1
PIAS2
PKP4
PLCD1
PML
POM121
PPHLN1
PPIA
PPP2R5C
PRDX6
PSMA6
RNF32
RPA1
RPL12
RPS20
RPS27A
SCAMP5
SCCPDH
SELENOV
SH3GL2
SMAD2
SNX3
SOX30
SPAG4
SPATA18
SUGT1
SUZ12
TCN2
TECR
TM2D3
TMEM120A
TP53BP1
TRAPPC8
UMPS
WDR48
XAGE1B
ZBTB8A
ZNF251
ZNF280B
Entrez ID
55802
22976
HPRD ID
06113
08491
Ensembl ID
ENSG00000272886
ENSG00000157212
Uniprot IDs
Q9NPI6
Q6ZW49
PDB IDs
2WX3
4B6H
3SQD
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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