RIOK2 and GFUS

Data Source:
BioGRID (two hybrid)

		RIOK2	GFUS
Description		RIO kinase 2	GDP-L-fucose synthase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Preribosome, Small Subunit Precursor	Cytosol Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Electron Transfer Activity GDP-4-dehydro-D-rhamnose Reductase Activity Identical Protein Binding GDP-mannose 3,5-epimerase Activity GDP-L-fucose Synthase Activity
	Biological Process	Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Protein Autophosphorylation Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Positive Regulation Of RRNA Processing	Leukocyte Cell-cell Adhesion Positive Regulation Of Endothelial Cell Migration GDP-mannose Metabolic Process Electron Transport Chain 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	GDP-fucose biosynthesis
Drugs		Fostamatinib	NADH
Diseases
GWAS		Chronic mountain sickness ( 31417607) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: APP CSNK2A1 GFUS PRDM16 RELA RPRD1A SMAD3	4 interacting genes: ID2 NEDD4 RIOK2 UBC
Entrez ID		55781	7264
HPRD ID		10193	00654
Ensembl ID		ENSG00000058729	ENSG00000104522
Uniprot IDs		Q9BVS4	A0A140VKC8 Q13630
PDB IDs		5DHF 6FDM 6FDN 6FDO 6G18 6G51 6HK6	4B8W 4B8Z 4BKP 4BL5 4E5Y
Enriched GO Terms of Interacting Partners?
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