RIOK2 and RPRD1A

Data Source:
BioGRID (two hybrid)

		RIOK2	RPRD1A
Description		RIO kinase 2	regulation of nuclear pre-mRNA domain containing 1A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Preribosome, Small Subunit Precursor	Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Complex Binding Protein Binding
	Biological Process	Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Protein Autophosphorylation Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Positive Regulation Of RRNA Processing	MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs		Fostamatinib
Diseases
GWAS		Chronic mountain sickness ( 31417607) Metabolite levels ( 23823483)	Drug-induced torsades de pointes ( 24223155) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		7 interacting genes: APP CSNK2A1 GFUS PRDM16 RELA RPRD1A SMAD3	13 interacting genes: BCAR3 FAM90A1 HGS KDM1A KPNA3 LONRF1 NXF1 RIOK2 RPRD1B SDCBP YWHAZ ZNF410 ZNF76
Entrez ID		55781	55197
HPRD ID		10193	10134
Ensembl ID		ENSG00000058729	ENSG00000141425
Uniprot IDs		Q9BVS4	A0A024RC37 A0A0C4DGQ6 Q96P16
PDB IDs		5DHF 6FDM 6FDN 6FDO 6G18 6G51 6HK6	4JXT 4NAC
Enriched GO Terms of Interacting Partners?
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