TBC1D23 and EIF3B

Data Source:
BioGRID (two hybrid)

		TBC1D23	EIF3B
Description		TBC1 domain family member 23	eukaryotic translation initiation factor 3 subunit B
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GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Cytoplasmic Vesicle WASH Complex	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Molecular Adaptor Activity
	Biological Process	Brain Development Vesicle-mediated Transport Neuron Projection Development Retrograde Transport, Endosome To Golgi Vesicle Tethering To Golgi Embryonic Brain Development	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
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Diseases
GWAS		Axial length ( 24144296) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		12 interacting genes: CAGE1 EHD2 EIF3B FAM214B KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-12 NOPCHAP1 SSBP3 STK11 WDR62	18 interacting genes: BHLHB9 BRCA1 EIF3A EIF3G EIF3I EIF3J EIF4G1 IL2RB LMO2 NDUFAB1 NF2 NREP PAIP1 PBX4 RPS6KB1 TBC1D23 TNNI1 UPF1
Entrez ID		55773	8662
HPRD ID		07727	06795
Ensembl ID		ENSG00000036054	ENSG00000106263
Uniprot IDs		Q9NUY8	A0A024R821 A4D210 P55884
PDB IDs		6JL7 6JM5	2KRB 2NLW 5K1H 6YBT 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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