ARFGAP1 and KDELR1

Data Source:
HPRD (in vivo, in vitro)

		ARFGAP1	KDELR1
Description		ADP ribosylation factor GTPase activating protein 1	KDEL endoplasmic reticulum protein retention receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Synapse	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	KDEL Sequence Binding Protein Binding ER Retention Sequence Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity	Protein Retention In ER Lumen Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport
Pathways		XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS
Interacting Genes		34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	12 interacting genes: ARF1 ARFGAP1 CCR9 COPB1 DLG2 DLG3 F2RL1 GPR35 KRT34 LIG4 PRKACA SEC23B
Entrez ID		55738	10945
HPRD ID		06443	00569
Ensembl ID		ENSG00000101199	ENSG00000105438
Uniprot IDs		Q53F62 Q8N6T3	P24390
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?
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