CEP72 and MCM10

Data Source:
HPRD (two hybrid)

		CEP72	MCM10
Description		centrosomal protein 72	minichromosome maintenance 10 replication initiation factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Centriolar Satellite	Nucleus Nucleoplasm Nucleolus Replication Fork Protection Complex
	Molecular Function	Protein Binding Identical Protein Binding	DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding Enzyme Binding Identical Protein Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Spindle Organization Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Gamma-tubulin Complex Localization Ciliary Basal Body-plasma Membrane Docking Regulation Of Protein Localization To Centrosome	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication Initiation Cellular Response To DNA Damage Stimulus Cell Population Proliferation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Activation of ATR in response to replication stress Activation of the pre-replicative complex
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Esophageal adenocarcinoma ( 27527254) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Ulcerative colitis ( 28067908 20228799) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658)	Nicotine dependence symptom count ( 25555482)
Interacting Genes		23 interacting genes: ATXN7 CATIP CHCHD3 FAM161A FAM90A1 GOLGA6L9 IGHM IL16 INCA1 KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417 ZNF688	38 interacting genes: APP CALCOCO2 CCDC85B CCND1 CCND3 CDC45 CDC5L CDC6 CDC7 CDK6 CDKN1A CDKN2A CEP70 CEP72 DAPK1 DPPA2 GOLGA2 HAUS1 HOOK2 IKBKG KLHL40 KRT15 MCM2 MCM3 MCM6 MCM7 NINL ORC2 ORC3 ORC4 PICK1 RECQL4 TNIP1 TRIM37 UBAC1 YWHAE ZBTB43 ZBTB8A
Entrez ID		55722	55388
HPRD ID		07685	11297
Ensembl ID		ENSG00000112877	ENSG00000065328
Uniprot IDs		Q9P209	Q7L590
PDB IDs
Enriched GO Terms of Interacting Partners?
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