SLF2 and SFMBT2

Data Source:
BioGRID (two hybrid)

		SLF2	SFMBT2
Description		SMC5-SMC6 complex localization factor 2	Scm like with four mbt domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Site Of Double-strand Break Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytosol Aggresome Nuclear Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding
	Biological Process	DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Protein Localization To Site Of Double-strand Break Positive Regulation Of Double-strand Break Repair	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Lung cancer ( 28604730)	Asthma (childhood onset) ( 31036433) Fasting blood insulin (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 32239398) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Monoclonal gammopathy of undetermined significance ( 30737484)
Interacting Genes		5 interacting genes: CALM1 OPTN PSMA1 SFMBT2 TRIM14	11 interacting genes: CLK1 L3MBTL3 LYPLA1 PHC1 SCMH1 SCML1 SCML2 SIAH1 SLF2 TFAP4 UBE2O
Entrez ID		55719	57713
HPRD ID		12581	18853
Ensembl ID		ENSG00000119906	ENSG00000198879
Uniprot IDs		Q8IX21	Q5VUG0
PDB IDs			1WJR
Enriched GO Terms of Interacting Partners?
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