SFMBT2 and UBE2O

Data Source:
BioGRID (two hybrid)

		SFMBT2	UBE2O
Description		Scm like with four mbt domains 2	ubiquitin conjugating enzyme E2 O
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Aggresome Nuclear Body Nuclear Speck Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding	RNA Binding Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated	Protein Monoubiquitination Negative Regulation Of Endopeptidase Activity Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Protein K63-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Fasting blood insulin (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 32239398) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Monoclonal gammopathy of undetermined significance ( 30737484)	High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mitochondrial DNA levels ( 25240745) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: CLK1 L3MBTL3 LYPLA1 PHC1 SCMH1 SCML1 SCML2 SIAH1 SLF2 TFAP4 UBE2O	17 interacting genes: APPL1 BAP1 CPNE1 CPNE2 CPNE4 HEXIM1 ITCH MAF MDM2 PRKN RNF10 RNF31 SFMBT2 SHBG TRIM27 UBC UBE2D3
Entrez ID		57713	63893
HPRD ID		18853	10928
Ensembl ID		ENSG00000198879	ENSG00000175931
Uniprot IDs		Q5VUG0	Q9C0C9
PDB IDs		1WJR
Enriched GO Terms of Interacting Partners?
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