NLRP2 and PYDC2

Data Source:
HPRD (in vitro, in vivo)

		NLRP2	PYDC2
Description		NLR family pyrin domain containing 2	pyrin domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Cytoplasm Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	Protein Binding ATP Binding Pyrin Domain Binding	Protein Binding
	Biological Process	Apoptotic Process Inflammatory Response Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Innate Immune Response	Inflammatory Response Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-1 Beta Production Innate Immune Response Negative Regulation Of Inflammatory Response Negative Regulation Of NLRP3 Inflammasome Complex Assembly Negative Regulation Of NIK/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Venous thromboembolism ( 31420334)	Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		4 interacting genes: APP CARD8 FAF1 PYDC2	2 interacting genes: NLRP2 PYCARD
Entrez ID		55655	152138
HPRD ID		14805	19279
Ensembl ID		ENSG00000022556	ENSG00000253548
Uniprot IDs		A8K9G6 J3KN39 Q9NX02	Q56P42
PDB IDs
Enriched GO Terms of Interacting Partners?
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