PYDC2 and NLRP2

Data Source:
HPRD (in vitro, in vivo)

		PYDC2	NLRP2
Description		pyrin domain containing 2	NLR family pyrin domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromosome, Telomeric Region Cytoplasm Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding ATP Binding Pyrin Domain Binding
	Biological Process	Inflammatory Response Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-1 Beta Production Innate Immune Response Negative Regulation Of Inflammatory Response Negative Regulation Of NLRP3 Inflammasome Complex Assembly Negative Regulation Of NIK/NF-kappaB Signaling	Apoptotic Process Inflammatory Response Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Serum metabolite concentrations in chronic kidney disease ( 29545352)	Inflammatory bowel disease ( 23128233) Venous thromboembolism ( 31420334)
Interacting Genes		2 interacting genes: NLRP2 PYCARD	4 interacting genes: APP CARD8 FAF1 PYDC2
Entrez ID		152138	55655
HPRD ID		19279	14805
Ensembl ID		ENSG00000253548	ENSG00000022556
Uniprot IDs		Q56P42	A8K9G6 J3KN39 Q9NX02
PDB IDs
Enriched GO Terms of Interacting Partners?
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