NHP2 and NOP10

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		NHP2	NOP10
Description		NHP2 ribonucleoprotein	NOP10 ribonucleoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Telomerase Holoenzyme Complex Sno(s)RNA-containing Ribonucleoprotein Complex Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex	Nucleoplasm Telomerase Holoenzyme Complex Sno(s)RNA-containing Ribonucleoprotein Complex Nuclear Body Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex
	Molecular Function	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding
	Biological Process	Cleavage Involved In RRNA Processing Maturation Of LSU-rRNA Telomere Maintenance Via Telomerase RRNA Pseudouridine Synthesis SnRNA Pseudouridine Synthesis Positive Regulation Of Telomerase RNA Localization To Cajal Body	SnoRNA Guided RRNA Pseudouridine Synthesis Pseudouridine Synthesis Telomere Maintenance Via Telomerase RRNA Pseudouridine Synthesis SnRNA Pseudouridine Synthesis Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol	Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
Drugs
Diseases		Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)	Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)
GWAS		Platelet count ( 29403010)
Interacting Genes		9 interacting genes: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 NOS1AP PRNP UTP23	3 interacting genes: CABP2 MEOX2 NHP2
Entrez ID		55651	55505
HPRD ID		07570	07571
Ensembl ID		ENSG00000145912	ENSG00000182117
Uniprot IDs		J3QSY4 Q9NX24	Q9NPE3
PDB IDs
Enriched GO Terms of Interacting Partners?
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