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NHP2

Description NHP2 ribonucleoprotein
Image No pdb structure
GO Annotations Cellular Component
  • Chromosome, Telomeric Region
  • Nucleoplasm
  • Telomerase Holoenzyme Complex
  • Sno(s)RNA-containing Ribonucleoprotein Complex
  • Box H/ACA SnoRNP Complex
  • Box H/ACA ScaRNP Complex
  • Box H/ACA Telomerase RNP Complex
Molecular Function
  • RNA Binding
  • Protein Binding
  • Box H/ACA SnoRNA Binding
  • Telomerase RNA Binding
Biological Process
  • Cleavage Involved In RRNA Processing
  • Maturation Of LSU-rRNA
  • Telomere Maintenance Via Telomerase
  • RRNA Pseudouridine Synthesis
  • SnRNA Pseudouridine Synthesis
  • Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways
  • Telomere Extension By Telomerase
  • rRNA modification in the nucleus and cytosol
Drugs
Diseases
  • Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)
GWAS
  • Platelet count ( 29403010)
Interacting Genes 9 interacting genes: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 NOS1AP PRNP UTP23
Entrez ID 55651
HPRD ID 07570
Ensembl ID ENSG00000145912
Uniprot IDs J3QSY4 Q9NX24
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025