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STAP2 and STAT5A
Data Source:
HPRD
(in vivo)
STAP2
STAT5A
Description
signal transducing adaptor family member 2
signal transducer and activator of transcription 5A
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Chromatin
Nucleoplasm
Cytosol
Molecular Function
Protein Binding
Signaling Adaptor Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Biological Process
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Endothelial Cell Proliferation
Regulation Of Transcription By RNA Polymerase II
Defense Response
Receptor Signaling Pathway Via JAK-STAT
Lactation
Cytokine-mediated Signaling Pathway
Taurine Metabolic Process
Interleukin-15-mediated Signaling Pathway
Reelin-mediated Signaling Pathway
Interleukin-2-mediated Signaling Pathway
Interleukin-7-mediated Signaling Pathway
Interleukin-9-mediated Signaling Pathway
Regulation Of Multicellular Organism Growth
Regulation Of Cell Population Proliferation
Response To Peptide Hormone
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Pathways
PTK6 Activates STAT3
Prolactin receptor signaling
Nuclear signaling by ERBB4
Interleukin-7 signaling
Interleukin-7 signaling
Signaling by SCF-KIT
Signaling by cytosolic FGFR1 fusion mutants
Downstream signal transduction
Signaling by Leptin
Interleukin-3, Interleukin-5 and GM-CSF signaling
Interleukin-3, Interleukin-5 and GM-CSF signaling
Interleukin-20 family signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-2 signaling
Interleukin-21 signaling
Erythropoietin activates STAT5
STAT5 Activation
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
STAT5 activation downstream of FLT3 ITD mutants
Signaling by FLT3 fusion proteins
Growth hormone receptor signaling
Growth hormone receptor signaling
Drugs
Diseases
GWAS
Tea consumption (
31046077
)
Asthma (childhood onset) (
31036433
)
Crohn's disease (
28067908
)
Heel bone mineral density (
30598549
)
Inflammatory bowel disease (
27569725
28067908
23128233
)
Low density lipoprotein cholesterol levels (
32154731
)
Ulcerative colitis (
28067908
)
Interacting Genes
18 interacting genes:
BLK
BMP4
CBL
CHUK
CSF1R
EGFR
IKBKB
JAK2
KEAP1
MLH1
MYD88
PTK6
SRC
STAT3
STAT5A
STAT5B
TXK
YES1
72 interacting genes:
AQP11
BMX
BRCA1
BRCA2
BTK
CBL
CCR5
CD247
CEBPB
CENPJ
CRK
CRKL
CSNK2B
CTLA4
CYP2C9
EGFR
EP300
EPAS1
EPOR
ERBB4
ESR1
ESR2
FBXW7
FN1
GHR
GLUD1
GNB2
HELZ
IL2RB
IL2RG
IL7R
INSR
JAK1
JAK2
JAK3
KIT
LCK
MAGEA12
MAPK1
MAPK3
MRPS6
NCOR2
NMI
NR3C1
OLIG1
PDGFRA
PDGFRB
POM121C
POU2F1
PPIB
PPP2CA
PRMT1
PRTFDC1
PTPN1
PTPN11
PTPN2
RBMX
SHC1
SRC
STAP2
STAT1
STAT3
STAT5B
SYK
TCF12
TEK
TET2
TSLP
TXNDC11
UGT2B4
WASH2P
ZNF596
Entrez ID
55620
6776
HPRD ID
07430
03301
Ensembl ID
ENSG00000178078
ENSG00000126561
Uniprot IDs
Q9UGK3
A0A384N5W4
A8K6I5
K7EK35
P42229
Q59GY7
PDB IDs
2EL8
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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