DOCK10 and LURAP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DOCK10	LURAP1
Description		dedicator of cytokinesis 10	leucine rich adaptor protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Dendritic Spine Extracellular Exosome	Cytoplasm Cytosol Actomyosin Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	B Cell Homeostasis Marginal Zone B Cell Differentiation Small GTPase Mediated Signal Transduction Regulation Of Cell Migration Positive Regulation Of GTPase Activity Dendritic Spine Morphogenesis	Positive Regulation Of Cytokine Production Cell Migration Actomyosin Structure Organization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) IgE levels in asthmatics (D.p. specific) ( 23967269) Mean platelet volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) Response to bupropion and depression ( 27622933) Response to exercise (triglyceride level interaction) ( 26491034) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)	Body mass index ( 26426971)
Interacting Genes		4 interacting genes: CCDC102B LURAP1 MAGEA11 RHOJ	22 interacting genes: ABI2 AMOT BLOC1S6 CCDC112 CCDC185 CSNK1D DOCK10 DTNB HAUS1 HGS HMG20A KRT3 PRPF31 SHFL SNAP29 TCEANC THAP7 TPM3 TXLNB U2AF2 ZNF417 ZNF821
Entrez ID		55619	541468
HPRD ID		10919	18478
Ensembl ID		ENSG00000135905	ENSG00000171357
Uniprot IDs		Q96BY6	Q96LR2
PDB IDs		6TKY 6TKZ 6TM1
Enriched GO Terms of Interacting Partners?
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