PPP1R9A and PPP1R2

Data Source:
HPRD (in vitro, in vivo)

		PPP1R9A	PPP1R2
Description		protein phosphatase 1 regulatory subunit 9A	protein phosphatase 1 regulatory inhibitor subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Postsynaptic Density Actin Cytoskeleton Filopodium Dendrite Cortical Actin Cytoskeleton Neuromuscular Junction Neuronal Cell Body Dendritic Spine Neck Postsynaptic Actin Cytoskeleton Glutamatergic Synapse Growth Cone Lamellipodium
	Molecular Function	Protein Binding Protein C-terminus Binding Protein Phosphatase 1 Binding Protein Kinase Binding Protein Domain Specific Binding Identical Protein Binding Ion Channel Binding Actin Filament Binding GTPase Binding	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Actin Filament Organization Aging Positive Regulation Of Neuron Projection Development Calcium-mediated Signaling Regulation Of Actin Filament Polymerization Neuron Projection Development Positive Regulation Of Protein Kinase Activity Regulation Of Filopodium Assembly Negative Regulation Of Stress Fiber Assembly Regulation Of Synapse Structural Plasticity Regulation Of Synapse Assembly Excitatory Postsynaptic Potential Positive Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Cellular Response To Toxic Substance Postsynaptic Actin Cytoskeleton Organization Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Long-term Synaptic Depression Negative Regulation Of Spontaneous Neurotransmitter Secretion	Glycogen Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of Signal Transduction Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Waist circumference ( 28552196)
Interacting Genes		10 interacting genes: ACTG1 PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9B PRKAR1B RPS6KA1 RPS6KB1 TGOLN2	12 interacting genes: CDK5 CSNK2A1 CSNK2A2 GSK3B LMTK2 NEK2 PPP1CA PPP1CC PPP1R9A PPP1R9B TERF2IP TINF2
Entrez ID		55607	5504
HPRD ID		16000	03478
Ensembl ID		ENSG00000158528	ENSG00000184203
Uniprot IDs		A4D1I0 B7ZLX4 Q9ULJ8	P41236
PDB IDs		1WF8
Enriched GO Terms of Interacting Partners?
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