OTUD5 and SUB1

Data Source:
BioGRID (pull down)

		OTUD5	SUB1
Description		OTU deubiquitinase 5	SUB1 regulator of transcription
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GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Extracellular Exosome
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Cysteine-type Peptidase Activity Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Type I Interferon Production Response To Lipopolysaccharide Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter SMAD Protein Signal Transduction
Pathways		Ovarian tumor domain proteases Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		12 interacting genes: ARPC3 NEDD8 NONO PDCD5 POLR2A POLR2B POLR2C SUB1 TP53 TRAF3 UBC UBR5	22 interacting genes: ADAP1 APP CBX5 CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 OTUD5 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST SDCBP SP1 TAF1 TBP TP53
Entrez ID		55593	10923
HPRD ID		06488	02737
Ensembl ID		ENSG00000068308	ENSG00000113387
Uniprot IDs		A0A024QZ09 Q96G74	P53999 Q6IBA2
PDB IDs		3PFY 3TMO 3TMP	1PCF 2C62 2PHE 4USG 6YCS
Enriched GO Terms of Interacting Partners?
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