SUB1 and OTUD5

Data Source:
BioGRID (pull down)

		SUB1	OTUD5
Description		SUB1 regulator of transcription	OTU deubiquitinase 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Extracellular Exosome	Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Cysteine-type Peptidase Activity Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter SMAD Protein Signal Transduction	Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Type I Interferon Production Response To Lipopolysaccharide Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways			Ovarian tumor domain proteases Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		22 interacting genes: ADAP1 APP CBX5 CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 OTUD5 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST SDCBP SP1 TAF1 TBP TP53	12 interacting genes: ARPC3 NEDD8 NONO PDCD5 POLR2A POLR2B POLR2C SUB1 TP53 TRAF3 UBC UBR5
Entrez ID		10923	55593
HPRD ID		02737	06488
Ensembl ID		ENSG00000113387	ENSG00000068308
Uniprot IDs		P53999 Q6IBA2	A0A024QZ09 Q96G74
PDB IDs		1PCF 2C62 2PHE 4USG 6YCS	3PFY 3TMO 3TMP
Enriched GO Terms of Interacting Partners?
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