PRIM1 and SLC26A8

Data Source:
BioGRID (biochemical)

		PRIM1	SLC26A8
Description		DNA primase subunit 1	solute carrier family 26 member 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Alpha DNA Polymerase:primase Complex Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	DNA Primase Activity Protein Binding Metal Ion Binding	Chloride Channel Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity Oxalate Transmembrane Transporter Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication	Anion Transport Chloride Transport Multicellular Organism Development Sulfate Transport Bicarbonate Transport Oxalate Transport Flagellated Sperm Motility Sperm Capacitation Meiotic Cell Cycle Sulfate Transmembrane Transport Chloride Transmembrane Transport
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma ( 31619474) Height ( 31562340) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menopause (age at onset) ( 22267201 26414677) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010)	Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811)
Interacting Genes		4 interacting genes: MDC1 MRPL38 PRIM2 TP53	1 interacting genes: RACGAP1
Entrez ID		5557	116369
HPRD ID		08899	12241
Ensembl ID		ENSG00000198056	ENSG00000112053
Uniprot IDs		P49642	A0A024RCV0 Q96RN1
PDB IDs		4BPU 4BPW 4BPX 4LIK 4LIL 4MHQ 4RR2 5EXR 6R4S 6R4T 6R4U 6R5D 6R5E 6RB4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?