KLK15 and DYNLT1

Data Source:
BioGRID (two hybrid)

		KLK15	DYNLT1
Description		kallikrein related peptidase 15	dynein light chain Tctex-type 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Secretory Granule	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Proteolysis	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Celiac disease ( 23936387) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Prostate-specific antigen levels ( 25434496)
Interacting Genes		4 interacting genes: DYNLT1 HOOK2 KRTAP10-3 TRIP6	50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		55554	6993
HPRD ID		07490	15987
Ensembl ID		ENSG00000174562	ENSG00000146425
Uniprot IDs		A0A6B7HBY5 M0R0D7 Q6UBM2 Q9H2R5	P63172
PDB IDs			5JPW
Enriched GO Terms of Interacting Partners?
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