GPRC5D and ERC1

Data Source:
BioGRID (affinity chromatography technology)

		GPRC5D	ERC1
Description		G protein-coupled receptor class C group 5 member D	ELKS/RAB6-interacting/CAST family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Ciliary Basal Body Presynaptic Membrane Synapse Cytoskeleton Of Presynaptic Active Zone
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Protein Binding PDZ Domain Binding Small GTPase Binding Leucine Zipper Domain Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Neuromuscular Synaptic Transmission Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Regulation Of Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867)
Interacting Genes		30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	9 interacting genes: APP DNAJC5 ITSN2 PPFIA1 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		55507	23085
HPRD ID		07604	06181
Ensembl ID		ENSG00000111291	ENSG00000082805
Uniprot IDs		Q9NZD1	G8JLD3 Q8IUD2 X6RLX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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