WDR33 and NEK9

Data Source:
BioGRID (affinity chromatography technology)

		WDR33	NEK9
Description		WD repeat domain 33	NIMA related kinase 9
Image
GO Annotations	Cellular Component	Fibrillar Center Collagen Trimer Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleus Centrosome Cytosol
	Molecular Function	RNA Binding	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Postreplication Repair Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Export From Nucleus Spermatogenesis MRNA 3'-end Processing	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS		Coronary artery calcification ( 23870195) Coronary artery disease ( 29212778) White blood cell count ( 32888494)	Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		19 interacting genes: CDK4 EEF1G GIT1 KAT7 MIR19A MIR19B1 MIR34B MIR92A2 PFN2 PRMT1 RBM48 SH3GL3 TGFBR1 TP53 UBC UTP14A WWOX ZBTB16 ZHX1	10 interacting genes: BICD2 CSN2 MBP NEK6 NEK7 NEK8 RAN SSRP1 SUPT16H TTN
Entrez ID		55339	91754
HPRD ID		11680	11386
Ensembl ID		ENSG00000136709	ENSG00000119638
Uniprot IDs		Q9C0J8	Q6PKF2 Q8TD19
PDB IDs		6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO	3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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