SYNJ2BP and SMOC1

Data Source:
BioGRID (two hybrid)

		SYNJ2BP	SMOC1
Description		synaptojanin 2 binding protein	SPARC related modular calcium binding 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane	Basement Membrane Extracellular Space
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Heparin Binding Extracellular Matrix Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis	Eye Development Cell Differentiation Extracellular Matrix Organization Regulation Of Osteoblast Differentiation Limb Development
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Blood protein levels ( 30072576 29875488) Bone mineral density ( 24249740) Daytime sleep phenotypes ( 27126917) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Peripheral artery disease ( 31285632) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252) Refractive error ( 32231278) Triglyceride levels ( 30108155) Tuberculosis ( 24057671)
Interacting Genes		33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1	8 interacting genes: CYSRT1 KRTAP1-1 KRTAP10-3 KRTAP10-8 NOTCH2NLA NR4A3 TCF4 VGLL3
Entrez ID		55333	64093
HPRD ID		15455	12244
Ensembl ID		ENSG00000213463	ENSG00000198732
Uniprot IDs		A0A024R670 P57105	A0A024R6E0 Q9H4F8
PDB IDs		2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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