ABCF3 and FCHSD2

Data Source:
BioGRID (two hybrid)

		ABCF3	FCHSD2
Description		ATP binding cassette subfamily F member 3	FCH and double SH3 domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Clathrin-coated Pit Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Protein Binding ATP Binding ATPase Activity Cadherin Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Defense Response To Virus	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Major depressive disorder ( 22472876) Subcortical volume (MOSTest) ( 32665545)	Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)
Interacting Genes		20 interacting genes: ACIN1 CCDC33 DLEU1 DNALI1 FBXO7 FCHSD2 HIRIP3 LAMTOR1 MDFI MOCS2 NOA1 PSME3 RBPMS SLC35E1 SPP1 TBPL1 THAP1 TOE1 TRIM14 TRIM27	52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C2orf73 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587
Entrez ID		55324	9873
HPRD ID		12404	13321
Ensembl ID		ENSG00000161204	ENSG00000137478
Uniprot IDs		A0A0S2Z5L1 Q9NUQ8	O94868
PDB IDs			2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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