CCDC91 and GGA1

Data Source:
HPRD (in vitro, in vivo)

		CCDC91	GGA1
Description		coiled-coil domain containing 91	golgi associated, gamma adaptin ear containing, ARF binding protein 1
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GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Identical Protein Binding	Molecular_function Protein Binding Small GTPase Binding
	Biological Process	Protein Transport Golgi To Lysosome Transport	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane
Pathways			TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone ultrasound measurement (velocity of sound) ( 28472463) Brain morphology (MOSTest) ( 32665545) Breast size ( 27182965) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 23563607 31562340) High light scatter reticulocyte count ( 32888494) Hip circumference adjusted for BMI ( 25673412) Immature fraction of reticulocytes ( 32888494) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function (FEV1) ( 28166213 26635082) Lung function (FVC) ( 28166213 26635082 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Narrowest width of the femoral neck ( 30888730) Obesity-related traits ( 23251661) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis of the hand ( 28855172) Peak expiratory flow ( 30804560) Reticulocyte fraction of red cells ( 32888494) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)	Health literacy ( 31250787)
Interacting Genes		11 interacting genes: AP1G1 CDC37 DAPK2 ECT2 EWSR1 GGA1 GGA2 LNX1 PRR5L SYNRG TESC	40 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR F8 GGA2 GGA3 IGF2R ING5 LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18
Entrez ID		55297	26088
HPRD ID		16905	12078
Ensembl ID		ENSG00000123106	ENSG00000100083
Uniprot IDs		A0A024RAW6 Q05D28 Q7Z6B0	Q9UJY5
PDB IDs		1OM9	1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
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