GGA1 and AP1AR

Data Source:
HPRD (in vitro)

		GGA1	AP1AR
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	adaptor related protein complex 1 associated regulatory protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Endosome Early Endosome Late Endosome Golgi Apparatus Cytosol Transport Vesicle
	Molecular Function	Molecular_function Protein Binding Small GTPase Binding	Kinesin Binding AP-1 Adaptor Complex Binding
	Biological Process	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane	Negative Regulation Of Receptor Recycling Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Protein Localization Vesicle Targeting, Trans-Golgi To Endosome Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Motility
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)	Body mass index ( 26426971)
Interacting Genes		40 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR F8 GGA2 GGA3 IGF2R ING5 LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18	3 interacting genes: AP1G1 GGA1 KLC1
Entrez ID		26088	55435
HPRD ID		12078	12824
Ensembl ID		ENSG00000100083	ENSG00000138660
Uniprot IDs		Q9UJY5	A0A024RDI1 Q63HQ0
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
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