KLHL26 and FOXH1

Data Source:
BioGRID (two hybrid)

		KLHL26	FOXH1
Description		kelch like family member 26	forkhead box H1
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Activin Responsive Factor Complex
	Molecular Function	Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding SMAD Binding Androgen Receptor Binding Co-SMAD Binding R-SMAD Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Heart Looping Secondary Heart Field Specification Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Ventricular Trabecula Myocardium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Embryonic Heart Tube Anterior/posterior Pattern Specification Aorta Morphogenesis Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axial Mesoderm Development Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Pathways			Signaling by NODAL Signaling by Activin
Drugs
Diseases
GWAS		Gastroesophageal reflux disease ( 31527586)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988) General cognitive ability ( 29844566)
Interacting Genes		14 interacting genes: ACIN1 ANKS1A AQP1 ENKD1 FOXH1 INCA1 KCTD9 NUDT22 OTX1 PITX1 POGZ PRR35 UBQLN4 ZIC1	67 interacting genes: AOC1 ARID5A ATP23 ATXN1L BATF2 C10orf55 C11orf1 C19orf54 CEACAM6 CRX CRYBA1 CYSRT1 DAZAP2 DRAP1 FAM168B FAM83A FOXD2 FOXG1 HDHD3 HEY1 HLX HOXA1 HSF4 KLHL26 KRTAP11-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP7-1 LASP1 MAGED1 MGAT5B MSX2 NKX2-5 NOTO OXER1 PLA2G10 PNMA5 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM46 RBPMS2 RNF144B SERGEF SMAD2 SMAD3 SMAD4 SOX14 SOX4 TEKT5 TFG TLX3 TSC1 UBAP2 UFSP1 ZC3H10 ZIC1 ZNF34 ZNF503
Entrez ID		55295	8928
HPRD ID		07728	04689
Ensembl ID		ENSG00000167487	ENSG00000160973
Uniprot IDs		A0A024R7N5 M0R1N0 M0R1P3 Q53HC5	O75593
PDB IDs			5XOC
Enriched GO Terms of Interacting Partners?
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