PSPC1 and NONO

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo)

		PSPC1	NONO
Description		paraspeckle component 1	non-POU domain containing octamer binding
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding RNA Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Rhythmic Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		13 interacting genes: DISC1 ESR1 KRT31 KRTAP13-1 LRIF1 LZTS1 NONO NUDT21 SFPQ TCERG1 WBP4 ZRANB1 ZSCAN5B	115 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERCC6 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYC MYCN ORC5 OTUD5 PIN1 PLEKHF2 POLR1H POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SUMO2 SYNPO TCERG1 UBE2D1 UBE2I WBP4
Entrez ID		55269	4841
HPRD ID		10172	02098
Ensembl ID		ENSG00000121390	ENSG00000147140
Uniprot IDs		Q8WXF1	A0A0S2Z4Z9 Q15233
PDB IDs		3SDE 5IFN 5WPA	3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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