ASXL2 and MBD6

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		ASXL2	MBD6
Description		ASXL transcriptional regulator 2	methyl-CpG binding domain protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm PR-DUB Complex	Fibrillar Center Nucleus Nucleoplasm Chromosome Chromocenter
	Molecular Function	DNA Binding Chromatin Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Transcription, DNA-templated Animal Organ Morphogenesis Positive Regulation Of Lipid Storage Protein Deubiquitination Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Protein Deubiquitination
Pathways		UCH proteinases	UCH proteinases
Drugs
Diseases
GWAS		Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Heel bone mineral density ( 30598549) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: APP MBD6 PRPF40A UBC UBE2E1 UBE2E2 UBE2E3	5 interacting genes: ASXL2 ATXN1L DUSP12 NCK2 RBM10
Entrez ID		55252	114785
HPRD ID		10676	11296
Ensembl ID		ENSG00000143970	ENSG00000166987
Uniprot IDs		Q76L83	A0A024RBA3 Q6P0P0 Q96DN6
PDB IDs
Enriched GO Terms of Interacting Partners?
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