STEAP3 and PKMYT1

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		STEAP3	PKMYT1
Description		STEAP3 metalloreductase	protein kinase, membrane associated tyrosine/threonine 1
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane	Golgi Membrane Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding Cupric Reductase Activity Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Regulation Of Apoptotic Process Iron Ion Homeostasis	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Phosphorylation Regulation Of Mitotic Nuclear Division Negative Regulation Of Phosphatase Activity Meiotic Cell Cycle
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Transferrin endocytosis and recycling	Polo-like kinase mediated events Cyclin A/B1/B2 associated events during G2/M transition Cyclin A/B1/B2 associated events during G2/M transition G2/M DNA replication checkpoint
Drugs			Fostamatinib
Diseases
GWAS		Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)	Metabolic syndrome ( 20694148)
Interacting Genes		6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1	24 interacting genes: ABHD16A BCL2 CCNB1 CD3E CD79A CDK1 CLDN8 ELOVL4 FATE1 LIME1 LRRC25 MAPK10 MAPK8 MFSD14B MFSD5 PIN1 PLK1 RETREG3 SLC10A1 SLC30A8 STEAP3 TMEM101 TMEM229B TMX2
Entrez ID		55240	9088
HPRD ID		10285	03920
Ensembl ID		ENSG00000115107	ENSG00000127564
Uniprot IDs		A1P3F0 B8ZZX6 Q658P3	Q0IJ49 Q99640
PDB IDs		2VNS 2VQ3	3P1A 5VCV 5VCW 5VCX 5VCY 5VCZ 5VD0 5VD1 5VD3
Enriched GO Terms of Interacting Partners?
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