ARL8B and VPS41

Data Source:
BioGRID (pull down)

		ARL8B	VPS41
Description		ADP ribosylation factor like GTPase 8B	VPS41 subunit of HOPS complex
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Vacuolar Membrane Membrane Midbody Late Endosome Membrane Synapse Spindle Midzone Extracellular Exosome Axon Cytoplasm	Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Clathrin Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Alpha-tubulin Binding Beta-tubulin Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Cell Cycle Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Cell Division	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483)	Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		11 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 SLC30A8 TGFBR1 TMEM14B TUBB VPS41	12 interacting genes: AKTIP AP3D1 APP ARL8B HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B
Entrez ID		55207	27072
HPRD ID		12483	10402
Ensembl ID		ENSG00000134108	ENSG00000006715
Uniprot IDs		Q9NVJ2	P49754
PDB IDs		2AL7
Enriched GO Terms of Interacting Partners?
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