ARL8B and DLEU1

Data Source:
HPRD (two hybrid)

		ARL8B	DLEU1
Description		ADP ribosylation factor like GTPase 8B	deleted in lymphocytic leukemia 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Vacuolar Membrane Membrane Midbody Late Endosome Membrane Synapse Spindle Midzone Extracellular Exosome Axon Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Cell Cycle Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Cell Division
Pathways
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483)	Adiponectin levels ( 26299439) Adiponectin levels (BMI-adjusted) ( 26299439) Aluminium levels ( 26025379) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Blood urea nitrogen levels ( 31152163) Circulating odd-numbered chain saturated fatty acid levels (C19:0) ( 29738550) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) FEV1 ( 30804560) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 31562340 31217584) Hematocrit ( 29403010 32888494) Hemoglobin ( 29403010 32888494) Hip circumference adjusted for BMI ( 28552196) Lipoprotein (a) levels ( 30108283) Low density lipoprotein cholesterol levels ( 32154731) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244 21833088 27386562) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376) Plasma anti-thyroid peroxidase levels ( 29678681) Platelet distribution width ( 32888494) Primary biliary cholangitis ( 26394269) Prostate-specific antigen levels ( 28139693) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tumor necrosis factor alpha levels ( 31217265) Type 2 diabetes ( 30054458 30297969 32499647) Urinary albumin-to-creatinine ratio ( 31630189) Urinary magnesium excretion ( 31993563) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 SLC30A8 TGFBR1 TMEM14B TUBB VPS41	20 interacting genes: ABCD4 ABCF3 ARL8B CCDC90B CEP126 COPS6 EEF1A1 EEF1G GDF9 GOPC KAT5 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A
Entrez ID		55207	10301
HPRD ID		12483	16150
Ensembl ID		ENSG00000134108	ENSG00000176124
Uniprot IDs		Q9NVJ2
PDB IDs		2AL7
Enriched GO Terms of Interacting Partners?
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