CENPQ and CCDC6

Data Source:
BioGRID (two hybrid)

		CENPQ	CCDC6
Description		centromere protein Q	coiled-coil domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytosol Actin Cytoskeleton	Cytosol Cytoskeleton
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	CENP-A Containing Nucleosome Assembly Metaphase Plate Congression Positive Regulation Of Protein Localization To Kinetochore	Cytoskeleton Organization Biological_process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases			Thyroid cancer
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		14 interacting genes: AARD ABI2 ABI3 APP ATF2 BRME1 CCDC6 EMILIN1 HDAC7 HOMER1 KDM1A PLK1 SIKE1 SNX2	32 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CENPQ CREB1 CSNK2A1 CYTH4 FBXW7 GAS8 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 MTUS2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835
Entrez ID		55166	8030
HPRD ID		10788	09064
Ensembl ID		ENSG00000031691	ENSG00000108091
Uniprot IDs		Q7L2Z9	Q05CP8 Q16204
PDB IDs
Enriched GO Terms of Interacting Partners?
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