ANKZF1 and CTTN

Data Source:
HPRD (two hybrid)

		ANKZF1	CTTN
Description		ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1	cortactin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Ruffle Podosome Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Actin Filament Plasma Membrane Clathrin-coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Lamellipodium Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Dendritic Spine Intracellular Membrane-bounded Organelle Mitotic Spindle Midzone
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Ubiquitin-dependent ERAD Pathway Cellular Response To Hydrogen Peroxide	Intracellular Protein Transport Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Actin Filament Polymerization Regulation Of Axon Extension Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Positive Regulation Of Smooth Muscle Contraction Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Membrane Organization Dendritic Spine Maintenance Lamellipodium Organization Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			RHO GTPases activate PAKs Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APP AURKB CA2 CRK CTTN DNAJB11 NRSN2 STAT6 YWHAE	42 interacting genes: ACD ACTA1 ACTG1 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 CASP3 CD2AP CHD3 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 EGFR FER FGD1 GRB2 HAX1 HDAC6 HIP1R KCNA2 KEAP1 MET MYLK NHSL2 RPL9 SDC3 SH3BP2 SHANK2 SIRT1 SMURF1 SPRR2A SRC SYK TINF2 TJP1 TNK2 TRIM15 WASL WIPF1
Entrez ID		55139	2017
HPRD ID		07673	01268
Ensembl ID		ENSG00000163516	ENSG00000085733
Uniprot IDs		B8ZZS4 Q9H8Y5	A0A024R5M3 Q14247 Q53HG7
PDB IDs			1X69 2D1X
Enriched GO Terms of Interacting Partners?
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