WRAP53 and UBAP2

Data Source:
BioGRID (two hybrid)

		WRAP53	UBAP2
Description		WD repeat containing antisense to TP53	ubiquitin associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Telomerase Holoenzyme Complex Cytosol Cajal Body Nuclear Body Site Of Double-strand Break	P-body Nucleus Cytoplasm
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Identical Protein Binding Protein-containing Complex Binding Chaperone Binding Telomerase RNA Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	DNA Repair Telomere Maintenance Via Telomerase Viral Process Cajal Body Organization Telomere Formation Via Telomerase RNA Folding Positive Regulation Of DNA Repair Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Telomerase RNA Localization To Cajal Body Positive Regulation Of Establishment Of Protein Localization To Telomere Protein Localization To Cajal Body Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Negative Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Pathways		Telomere Extension By Telomerase Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Cognitive function ( 28093568)	Adult body size ( 32376654) Bipolar disorder ( 20351715) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 30054458 30297969)
Interacting Genes		2 interacting genes: UBAP2 VAC14	43 interacting genes: ASB13 ATPAF2 BANP C10orf55 CREM DAZAP2 EFHC1 FAM168B FNDC3B FOXH1 HGS IGFN1 ISX ITCH JMJD7 KANK2 KRTAP15-1 LCK MGAT5B NOXA1 NPAS2 NUTF2 OTX1 PLAC8 PLEKHB2 PPP2CA PRSS53 PSMB8 RBPMS RHOXF2 SHC3 SPAG8 TENT5B TEP1 TEX37 TFG TLE5 TP53BP1 TRAPPC6A VENTX VPS37C WRAP53 ZNF34
Entrez ID		55135	55833
HPRD ID		07670	06748
Ensembl ID		ENSG00000141499	ENSG00000137073
Uniprot IDs		Q9BUR4	B4DH66 B7Z7P2 Q5T6F2 Q9P0H6
PDB IDs
Enriched GO Terms of Interacting Partners?
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