UBAP2 and ISX

Data Source:
BioGRID (two hybrid)

		UBAP2	ISX
Description		ubiquitin associated protein 2	intestine specific homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT	Regulation Of Transcription By RNA Polymerase II Enteric Nervous System Development
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 20351715) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 30054458 30297969)	Age at first birth ( 27798627) Metabolite levels ( 23823483) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		43 interacting genes: ASB13 ATPAF2 BANP C10orf55 CREM DAZAP2 EFHC1 FAM168B FNDC3B FOXH1 HGS IGFN1 ISX ITCH JMJD7 KANK2 KRTAP15-1 LCK MGAT5B NOXA1 NPAS2 NUTF2 OTX1 PLAC8 PLEKHB2 PPP2CA PRSS53 PSMB8 RBPMS RHOXF2 SHC3 SPAG8 TENT5B TEP1 TEX37 TFG TLE5 TP53BP1 TRAPPC6A VENTX VPS37C WRAP53 ZNF34	5 interacting genes: GSC2 POU6F2 ROR2 UBAP2 UBC
Entrez ID		55833	91464
HPRD ID		06748	17957
Ensembl ID		ENSG00000137073	ENSG00000175329
Uniprot IDs		B4DH66 B7Z7P2 Q5T6F2 Q9P0H6	Q2M1V0
PDB IDs
Enriched GO Terms of Interacting Partners?
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