TRIM68 and NUDT16L1

Data Source:
BioGRID (two hybrid)

		TRIM68	NUDT16L1
Description		tripartite motif containing 68	nudix hydrolase 16 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Histone Acetyltransferase Binding Identical Protein Binding Protein Homodimerization Activity Androgen Receptor Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding SnoRNA Binding Protein Homodimerization Activity M7G(5')pppN Diphosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides Phosphodiesterase Decapping Endonuclease Activity
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Interferon-gamma-mediated Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway	MRNA Catabolic Process Sno(s)RNA Catabolic Process Dephosphorylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Malaria ( 31844061) Mean corpuscular hemoglobin ( 28548082) Mean corpuscular hemoglobin concentration ( 28548082) Mean corpuscular volume ( 28548082) Red blood cell count ( 28548082) White blood cell count ( 28548082)
Interacting Genes		14 interacting genes: DISC1 INCA1 KRTAP13-2 KRTAP13-3 LNX1 LZTFL1 NUDT16L1 POLR2G REL TCF4 TEPSIN UBE2D3 UBE2U ZBTB42	52 interacting genes: APP CABP2 ERBB2 FBXO7 HNRNPF HNRNPH1 IKZF3 INCA1 KRT31 LRRK1 METTL17 MIR122 MIR128-1 MIR128-2 MIR138-1 MIR141 MIR145 MIR18B MIR200C MIR21 MIR25 MIR31 MIR34A MIR34B MIR363 MIR451A MIR7-3 MIR9-1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4L NEK6 NTAQ1 PNMA1 RECK SMARCD1 TP53BP1 TRAF2 TRAF4 TRIM68 ZRANB1
Entrez ID		55128	84309
HPRD ID		11507	15309
Ensembl ID		ENSG00000167333	ENSG00000168101
Uniprot IDs		Q6AZZ1	B2RD96 Q9BRJ7 W4VSQ8
PDB IDs			3KVH 5ZCJ 6CO1 6D0L
Enriched GO Terms of Interacting Partners?
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