TRIM68 and ZBTB42

Data Source:
BioGRID (two hybrid)

		TRIM68	ZBTB42
Description		tripartite motif containing 68	zinc finger and BTB domain containing 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Histone Acetyltransferase Binding Identical Protein Binding Protein Homodimerization Activity Androgen Receptor Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Interferon-gamma-mediated Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Organ Development
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Malaria ( 31844061) Mean corpuscular hemoglobin ( 28548082) Mean corpuscular hemoglobin concentration ( 28548082) Mean corpuscular volume ( 28548082) Red blood cell count ( 28548082) White blood cell count ( 28548082)	HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		14 interacting genes: DISC1 INCA1 KRTAP13-2 KRTAP13-3 LNX1 LZTFL1 NUDT16L1 POLR2G REL TCF4 TEPSIN UBE2D3 UBE2U ZBTB42	50 interacting genes: ANKS1A ASB6 ATG9A BLK C1orf109 CABP5 CATSPER1 CCDC102B CDR2L CIDEC CINP CLIC3 CRY2 CTBP2 FMR1 GEM GOLGA2 GUCD1 HSD3B7 HSF2BP KANK2 KCTD9 KRT40 MAGOHB MAPK1 MDFI MID2 MKRN3 MYLIP NCK2 NDOR1 NOC4L OAZ3 OSGIN1 OSTF1 OTX1 PIN1 PLA2G6 POLR1C RAD51D SNX18 SPG21 TRAPPC2L TRIM68 TTC23 UBASH3A USHBP1 ZBTB16 ZBTB7B ZNF330
Entrez ID		55128	100128927
HPRD ID		11507	19441
Ensembl ID		ENSG00000167333	ENSG00000179627
Uniprot IDs		Q6AZZ1	B2RXF5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?