FANCL and CHCHD3

Data Source:
BioGRID (two hybrid, two hybrid)

		FANCL	CHCHD3
Description		FA complementation group L	coiled-coil-helix-coiled-coil-helix domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex	SAM Complex Nucleus Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome MIB Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Population Proliferation	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways		Fanconi Anemia Pathway	Mitochondrial protein import Cristae formation
Drugs
Diseases		Fanconi anemia
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Generalized epilepsy ( 30531953) HDL cholesterol levels ( 32203549) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077) Triglyceride levels ( 32203549) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)	Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		48 interacting genes: ACVR1 ANTKMT BMPR1B C19orf54 CADPS CERCAM CHCHD3 CTBP1 CTDSP1 CYB5R2 DDAH2 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GATA1 GGN GRN HDHD3 HES1 HOXD4 ID2 IHO1 IKZF3 KIFC3 KRTAP11-1 KRTAP13-2 KRTAP19-6 LZTS2 METTL15 MORN3 PCNA RBM45 RIMBP3 RNF11 SCNM1 SNF8 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W UFSP1 YPEL3 ZNF581	37 interacting genes: AMOTL2 ANKS1A ARMC7 BLZF1 C2CD6 CALCOCO2 CBY2 CCDC33 CCDC85B CEP72 CYSRT1 EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		55120	54927
HPRD ID		06997	13044
Ensembl ID		ENSG00000115392	ENSG00000106554
Uniprot IDs		Q9NW38	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs		3ZQS 4CCG
Enriched GO Terms of Interacting Partners?
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