CHCHD3 and EFHC1

Data Source:
BioGRID (two hybrid)

		CHCHD3	EFHC1
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	EF-hand domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleus Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome MIB Complex	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle
	Molecular Function	Protein Binding Phosphatase Binding Molecular Adaptor Activity	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding
	Biological Process	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways		Mitochondrial protein import Cristae formation
Drugs
Diseases			Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)	Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)
Interacting Genes		37 interacting genes: AMOTL2 ANKS1A ARMC7 BLZF1 C2CD6 CALCOCO2 CBY2 CCDC33 CCDC85B CEP72 CYSRT1 EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	67 interacting genes: C11orf45 C20orf85 CACNA1E CALCOCO2 CCDC130 CFAP161 CHCHD3 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN ZBED1
Entrez ID		54927	114327
HPRD ID		13044	10583
Ensembl ID		ENSG00000106554	ENSG00000096093
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	B2CKC5 Q5JVL4
PDB IDs
Enriched GO Terms of Interacting Partners?
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