TRMT12 and PRDM6

Data Source:
BioGRID (two hybrid)

		TRMT12	PRDM6
Description		tRNA methyltransferase 12 homolog	PR/SET domain 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus
	Molecular Function	Protein Binding TRNA Methyltransferase Activity TRNA 4-demethylwyosine Alpha-amino-alpha-carboxypropyltransferase Activity	Protein Binding Methyltransferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	TRNA Methylation	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Gene Expression Neurogenesis Methylation Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways		Synthesis of wybutosine at G37 of tRNA(Phe)
Drugs
Diseases
GWAS			Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618447) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 26390057 27841878 27618447 30578418)
Interacting Genes		3 interacting genes: LNX1 NUDT1 PRDM6	70 interacting genes: ABI2 AGXT AHCYL1 ANKS1A AQP1 ARID5A ATPAF2 ATXN7L2 BAG3 BANF2 BANP C1orf109 CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM214B FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A STK16 TCAF1 TEKT4 TLE5 TRIM14 TRMT12 TSGA10 TSGA10IP TSSK3 TTC23 UBASH3A USP54 ZFYVE26
Entrez ID		55039	93166
HPRD ID		07947	19698
Ensembl ID		ENSG00000183665	ENSG00000061455
Uniprot IDs		Q53H54	Q9NQX0
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?