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PPP1CB and PPP1R2C
Data Source:
BioGRID
(two hybrid)
PPP1CB
PPP1R2C
Description
protein phosphatase 1 catalytic subunit beta
PPP1R2C family member C
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Protein Phosphatase Type 1 Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Glycogen Granule
Extracellular Exosome
PTW/PP1 Phosphatase Complex
Cellular_component
Molecular Function
Protein Serine/threonine Phosphatase Activity
Protein Binding
Phosphatase Activity
Myosin Phosphatase Activity
Protein Kinase Binding
Metal Ion Binding
Myosin-light-chain-phosphatase Activity
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Glycogen Metabolic Process
Regulation Of Glycogen Biosynthetic Process
Regulation Of Glycogen Catabolic Process
Protein Dephosphorylation
Regulation Of Cell Adhesion
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Cell Division
Regulation Of Signal Transduction
Negative Regulation Of Phosphoprotein Phosphatase Activity
Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Triglyceride catabolism
Downregulation of TGF-beta receptor signaling
Regulation of PLK1 Activity at G2/M Transition
Circadian Clock
RHO GTPases activate PKNs
RHO GTPases activate PKNs
RHO GTPases activate CIT
RHO GTPases Activate ROCKs
RHO GTPases activate PAKs
RHO GTPases activate PAKs
RAF activation
Signaling by MRAS-complex mutants
Drugs
Diseases
GWAS
Body mass index (
25673413
)
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) (
30940143
)
Excessive sweating (
29895819
)
Heel bone mineral density (
30598549
28869591
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Pure non-grapefruit juice consumption (
31046077
)
Interacting Genes
50 interacting genes:
AATK
ACTN2
AURKA
BRCA1
C14orf180
CHCHD3
CLK1
CLOCK
CSNK2B
CSRNP1
CSRNP2
CYSRT1
DELEC1
FBXO7
H3-3A
H3C1
HOXA2
KANK2
KIF23
LMTK2
MAPT
MEOX2
NONO
PHACTR3
PPP1R11
PPP1R12B
PPP1R12C
PPP1R16A
PPP1R16B
PPP1R27
PPP1R2B
PPP1R2C
PPP1R3A
PPP1R3B
PPP1R3C
PPP1R7
PPP1R9A
PPP1R9B
PPP2R5C
PRKAR2A
PTK2
RB1
RORC
SH2D4A
SPATC1L
TLX1
TP53BP2
UBAC1
WBP11
ZFYVE9
3 interacting genes:
PPP1CA
PPP1CB
PPP1CC
Entrez ID
5500
80316
HPRD ID
11792
06593
Ensembl ID
ENSG00000213639
ENSG00000102055
Uniprot IDs
P62140
V9HW04
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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