INTS11 and SPIC

Data Source:
BioGRID (two hybrid)

		INTS11	SPIC
Description		integrator complex subunit 11	Spi-C transcription factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Integrator Complex Blood Microparticle	Chromatin Nucleus
	Molecular Function	Protein Binding Hydrolase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	SnRNA Processing SnRNA Transcription By RNA Polymerase II	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS			HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 28552196) Lung cancer in never smokers ( 28604730) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		38 interacting genes: ANXA7 C1orf94 CCDC120 CREB5 CSNK2B DSE FAM222B GPS2 HSF4 INTS9 KRTAP15-1 KRTAP26-1 LASP1 LENG8 MDFI OTX1 OXER1 PKN1 PLK1 PLSCR1 PLSCR4 PROP1 PRR35 SNRPC SPAG8 SPIC TBX6 TCF7L2 TFG TK1 TLX3 TRIP13 USP2 VAC14 VENTX YPEL3 ZC3H10 ZIC1	3 interacting genes: APP INTS11 MEOX1
Entrez ID		54973	121599
HPRD ID		13377	15438
Ensembl ID		ENSG00000127054	ENSG00000166211
Uniprot IDs		A0A024R073 A0A087WYI0 Q5TA45	Q8N5J4
PDB IDs		5V8W
Enriched GO Terms of Interacting Partners?
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