SPIC and INTS11

Data Source:
BioGRID (two hybrid)

		SPIC	INTS11
Description		Spi-C transcription factor	integrator complex subunit 11
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol Integrator Complex Blood Microparticle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Hydrolase Activity
	Biological Process	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	SnRNA Processing SnRNA Transcription By RNA Polymerase II
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 28552196) Lung cancer in never smokers ( 28604730) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: APP INTS11 MEOX1	38 interacting genes: ANXA7 C1orf94 CCDC120 CREB5 CSNK2B DSE FAM222B GPS2 HSF4 INTS9 KRTAP15-1 KRTAP26-1 LASP1 LENG8 MDFI OTX1 OXER1 PKN1 PLK1 PLSCR1 PLSCR4 PROP1 PRR35 SNRPC SPAG8 SPIC TBX6 TCF7L2 TFG TK1 TLX3 TRIP13 USP2 VAC14 VENTX YPEL3 ZC3H10 ZIC1
Entrez ID		121599	54973
HPRD ID		15438	13377
Ensembl ID		ENSG00000166211	ENSG00000127054
Uniprot IDs		Q8N5J4	A0A024R073 A0A087WYI0 Q5TA45
PDB IDs			5V8W
Enriched GO Terms of Interacting Partners?
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