EFHC1 and EIF4ENIF1

Data Source:
BioGRID (two hybrid)

		EFHC1	EIF4ENIF1
Description		EF-hand domain containing 1	eukaryotic translation initiation factor 4E nuclear import factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility	Protein Import Into Nucleus Negative Regulation Of Translation Stem Cell Population Maintenance Gene Silencing By RNA P-body Assembly Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation
Pathways
Drugs
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)	Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		67 interacting genes: C11orf45 C20orf85 CACNA1E CALCOCO2 CCDC130 CFAP161 CHCHD3 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN ZBED1	27 interacting genes: ATXN1 CDK6 CFAP206 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 L3MBTL2 MGAT5B OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 SPAG5 TCHP TTC19 TXLNA USP2
Entrez ID		114327	56478
HPRD ID		10583	10456
Ensembl ID		ENSG00000096093	ENSG00000184708
Uniprot IDs		B2CKC5 Q5JVL4	A0A024R1K0 Q9NRA8
PDB IDs			5ANR 6F9W 6X2R
Enriched GO Terms of Interacting Partners?
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